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The Powerball jackpot climbed to an estimated $1.09 billion after no one matched the game's six numbers Monday night and won the top prize, continuing a three-month-long winless streak.

The Blue Devils lost to Mercer University. Harvard, North Dakota State and Dayton are other underdogs who have pulled off surprises. Who's going to be upset next as basketball's March Madness sets in?

It's Derby Day in Kentucky, where days and weeks of anticipation will culminate in a race that lasts just over two minutes. When the starting gates open at 6:24 p.m. EDT, 19 horses will race on a wet Kentucky Derby track.

The CDC says the guidelines were posted to its website in error. The now-deleted updates were notable because so far the agency has stopped short of saying that the virus is airborne.

Maine's Secretary of State Shenna Bellows stated former President Donald Trump is not qualified to appear on the state's ballot under the 14th Amendment.

The unexpected star of the Australian Open is a 20-year-old tennis player who had never been outside of the U.S. before this tournament. Ben Shelton has played his way into the quarterfinals.

More than 2,000 were also injured after the 6.8-magnitude earthquake devastated homes in villages across the Atlas Mountains, as well as historical sites inside Marrakech city.

Facebook's parent company has released its newest AI for free. Trump says he's a target in the Jan. 6 insurrection investigation. An Oklahoma boy finds a piranha-like fish with human-like teeth.

NPR's Scott Detrow talks with labor reporter Josh Eidelson about a report he co-authored in Bloomberg Businessweek about the allegations of sexual harassment at SpaceX and the subsequent lawsuits.

A patient who came to regret the top surgery she got as a teen won a $2 million malpractice suit. Then, the American Society of Plastic Surgeons clarified its position that surgery is not recommended for transgender minors.