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Voters in five large states — Florida, North Carolina, Ohio, Illinois and Missouri — have their turn in the Republican and Democratic presidential primary contests Tuesday.

Three retired leaders of the Franciscan religious order have been charged with conspiracy and child endangerment for allegedly allowing a friar who was a known sexual predator to work in schools.

NPR's Robert Siegel talks with Debra Houry, director of the National Center for Injury Prevention and Control at the Centers for Disease Control and Prevention, about new opioid guidelines.

The Washington, D.C., metro system announced an emergency shutdown of its rail system starting at midnight Tuesday. The system will be closed for at least 29 hours for safety checks.

MSNBC's Joe Scarborough tweeted: "Smile. You just had a big night." Others commented that she was "shouting angrily." The response to their criticism on Twitter was swift.

The Washington, D.C., Metrorail system will be out of service for 29 hours due to potential faults in the electrical system. The subway is key for commuters, many of whom staff the federal government.

The Federal Reserve decided Wednesday to hold interest rates steady. The nation's central bank is watching for signs of overheating, but for now, says the economy is growing at a sustainable rate.

The front-runners in the Republican and Democratic presidential races each had a good night after Tuesday's slate of primaries. But primary season is not over yet.

NPR's Ari Shapiro talks to attorney Jamie Gorelick, who worked closely with Merrick Garland in the Bill Clinton-era Justice Department, about his background and record.

Gazans are increasingly taking on the Hamas government via social media, pressing for improved living conditions and increased cooperation with its Palestinian rival, Fatah.