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Also: Dr. Frank Jobe, pioneer of "Tommy John surgery," dies; Rep. Darrell Issa, R-Calif., apologizes for shutting off Democrat's microphone; and the LA Lakers suffer their worst defeat ever.

Also: Manhunt continues for ex-Los Angeles police officer suspected in three murders; Northeast and New England continue to dig out from weekend blizzard; Medal of Honor to be awarded at White House.

For 22 years, Jason Mazzola's life was defined by a genetic condition that can cause autism and intellectual disability. Then he started taking an experimental drug.

Weekend Edition guest host Don Gonyea speaks with Silvio Pietroluongo of Billboard Magazine about the recent changes to the formula for the "Hot 100" chart. Billboard now incorporates the number of views on YouTube to determine the top songs in the country.

President Bush arrives at the G-8 summit in Germany on Wednesday with a new plan on climate change as leaders of major industrialized countries gather for three days. But a bitter debate over missile defense looms over the talks.

Conscience or incompetence? Two competing narratives — along partisan lines — have emerged to explain the sudden departure of the head of the Federal Student Aid Office.

David Gura speaks to Cecilia Rouse, chair of the White House Council of Economic Advisers, about the health of the U.S. economy amid inflation, supply chain interruptions and labor shortages.

Shawn Fain has been UAW president for less than six months, elected in the first direct ballot where members picked their leadership. Now he's in the spotlight as the union starts to strike.

In entertainment news: Netflix has its day in the sun, receiving nominations for "House of Cards" and its reboot of "Arrested Development."

Also: Blast kills young girls in Afghanistan; Egypt's draft constitution gets support in first stage of voting; Sen. John Kerry expected to be tapped for secretary of state.